Preliminary study of the efficiency of primary filtration in the parenteral serum plant

Abstract

This work was conducted at the Plant Large Volume Parenteral Solutions in Plastic Bags (PSPGVBP) belonging to the Pharmaceutical Laboratory East. It is a preliminary study, which includes the study of the effectiveness of nongranular porous media for water treatment. Includes the study of the characteristics of the water supply and the filtration operation in granular media filter. For this equipment does not operate efficiently with respect to the characteristics of water. With the analysis of the turbidity of water at the inlet and outlet of the granular medium filter was determined that this is not the most suitable according to the needs of the process. Therefore substitution by a filter press, which ensures obtain a better water quality and increase the production capacity is proposed. The assays for the study of non-granular porous medium were performed in a handmade device whose operation similar to a filter press. Turbidity values obtained with the device were lower than those obtained from the granular filter, showing that it is more effective for water supply characteristics. In this paper the design of the equipment is not included because the experiments are to be performed in a pilot plant to simulate actual operating conditions so as to obtain a more realistic design of the filter press.